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KMID : 0877220020060010073
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Journal of Korean Epilepsy Society
2002 Volume.6 No. 1 p.73 ~ p.76
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Alternating Hemispheric Seizures with Migrating Brain Lesions in MELAS Syndrome
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Moon So-Young
Hong Seung-Bong
Song Young-Min
Ryoo Jae-Wook
Seo Dae-Won
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Abstract
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Epileptic seizure is a frequent sign of mitochondrial encephalopathies with lactic acidosis and stroke-like episodes (MELAS). We report a 21-year-old woman with MELAS who had alternating hemispheric seizures. Her brain MRI showed migratory short lasting lesions. Serial EEG recordings revealed epileptiform discharges, which occurred first on the right frontotemporal region but then switched to the left frontotemporal region concordant to her clinical and MRI manifestations. Migratory short lasting lesions may be helpful features for differentiating MELAS syndrome from other epileptic syndromes.
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KEYWORD
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MELAS, Seizures, MRI, Migratory
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